Nook On Lyne - Cumbria Working Labrador Breeder

DNA Health Tested Conditions

What is DNA?

DNA (Deoxyribonucleic Acid) is a long molecule that contains the biological instructions that makes each species unique. A gene is a section of the DNA that contains specific instructions. Dogs have 2 copies of all genes; one gene is inherited from the Dam and one from the Sire.

 

Conditions Tested

CNM Centronuclear Myopathy

CNM causes muscle weakness because of a deficiency of muscle fibres.

The clinical signs of CNM include reduced muscle tone, generalised muscle weakness, abnormal postures, odd gait, exercise intolerance and increased collapse when exposed to cold.

EIC Exercise Induced Collapse

This condition leads to a defect in nerve communication during intense exercise. In affected dogs, certain factors can trigger the collapse including the type of exercise, temperature and excitement of the dog.

The clinical signs of the condition are leg weakness followed by complete collapse after 5 to 20 minutes of strenuous activity. The severity can vary as such severely affected dogs may collapse with mild exercise and other dogs only exhibit collapse episodes sporadically.

SD2 Skeletal Dysplasia

SD2 is also known as dwarfism, it is a genetic condition that causes long bones to stop growing before being fully developed.

This particular type of dwarfism results in shortened front limbs and a raising dorsal line, but does not alter the torso length and depth.

HNPK Hereditary Nasal Parakeratosis

The condition causes the nose to dry out which leads to inflammation and continuous irritation of the skin on the nose.

Clinical signs include the nose surface to be dry, rough and eventually show a change in skin colour from a dark to lighter colour. Brown crusts may also develop on the surface and edge of the nose.

Prcd-PRA Progressive Retinal Atrophy

The condition is characterised by bilateral degeneration of the retina, causing progressive vision loss that culminates in total blindness.

DM Degenerative Myelopathy

This is a chronic progressive disease of the spinal cord resulting in eventual paralysis in older dogs typically between 7 and 14 years of age.

The disease initially affects the back legs and causes muscle weakness and a lack of coordination and initially may appear to be arthritis. As the disease progresses the dog may display symptoms such as incontinence. 

HUU Hyperuricosuria

This is a condition whereby uric acid does not dissolve easily in urine leading to elevated levels. The increased amount of Uric Acid can lead to the formation of stones.